ASSOCIATIONS OF SINGLE NUCLEOTIDE POLYMORPHISMSWITH BONE TUMORS IN PATIENTS IN RUSSIAN POPULATION
Ethiology and pathogenesis of bone tumors presenting a rare group of oncological diseases, are not fully understood. We have studied
6 single nucleotide polymorphisms rs7921 (GH1), rs7956547(IGF1), rs3761243(GNRH2), rs11737764(FGF2), rs6599400(FGFR3),
rs1690916(MDM2) associations with bone tumors in Russian patients. In our work we detect associations between 3 single nucleotide
polymorphisms: IGF1.rs7956547, GNRH2.rs3761243 and FGFR3.rs6599400 in patients with bone tumors.
Keywords:
bone tumors, single nucleotide polymorphisms